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KMID : 0369820100400010001
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Jorunal of Korean Pharmaceutical Sciences
2010 Volume.40 No. 1 p.1 ~ p.7
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Development of BioEquiv, a Computer Program for the Analysis of Bioequivalence
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Yoon Sang-Hoo
Hwang Nan-A
Lim Young-Chai
Lee Yong-Bok
Park Jung-Soo
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Abstract
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K- is a well known program for bioequivalence test using a design. Lee et al.(1998) and Park et al.(1999) suggested a and design, and also discussed their benefits. We developed a computer program, called BioEquiv, which can analyze some complex experimental designs such as, design and design including a standard design. This program is a user-friendly one and overcomes the disadvantages of K-. The detailed statistical formula and structure of BioEquiv are presented with some examples. The comparison between K- and BioEquiv are given with actual data analysis. BioEquiv is able to present a table of ANOVA test over some complex experimental designs. Moreover K- and BioEquiv draw the same result when data consists of design.
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KEYWORD
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Bioeqivalence, Computer program, Design of experiments, Statistical test
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